The "Innate Immunity and HIV Infection" team is working on innate immunity and on the mechanisms and control of immune activation in HIV infection. We are particularly interested in the role of subsets of regulatory T cells in the control of immune activation and T cell responses.
A research opportunity is available (early 2014) in our team to study the role of gamma delta double negative regulatory T cells in the control of immune activation in patients at different stages of HIV infection. The purpose is to characterize the phenotype and cytokine production pattern of gamma delta+ DN Tregs in HIV-infected patients and to identify their ability to decrease immune activation and/or to suppress immune responses.
The research project is already funded by the ANRS.
The applicant should have a Ph.D. degree and an experience in immunology. An expertise in cellular culture and cytometry and a previous experience in the study of chronic viral infections in humans will be particularly appreciated. Applicants are invited to submit their CV and reference letters to:
Professor Laurence WEISS
INSTITUT PASTEUR Unité de Régulation des Infections Rétrovirales
28 rue du Dr Roux 75724 Paris cedex 15 laurence.weiss@egp.aphp.fr
