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Latest Publications


A single-dose amber codon carrying live attenuated vaccine elicits pan-sarbecovirus immunity and blocks SARS-CoV-2 transmission
New publication in npj Vaccines from HKU-PRP's Co-Director Professor Leo Poon's team describing an innovative approach to developing a live attenuated SARS-CoV-2 vaccine candidate. The study demonstrates a novel approach to engineering a highly attenuated yet fully immunogenic SARS-CoV-2 vaccine candidate, showing: Near-sterile immunity in mice under stringent challenge conditions Broad protection against antigenically distinct variants and even SARS-CoV Complete block of onw


Congratulations to Dr. Hogan Wai on Completing the HKU-KCL Joint PhD Programme
During his studies in the HKU-KCL Joint PhD program, Hogan conducted multidisciplinary and cross-cultural research at the HKU-Pasteur Research Pole (HKU-PRP) and the King’s College London Centre for Host-Microbiome Interactions (KCL CHMI). His PhD was focused on deciphering the role of different Staphylococcus strains in atopic dermatitis (AD): "It is well-known that the skin microbiome of AD patients is different from that of healthy individuals. There is a difference in the


Causality for population health in the exposome era
Our recent paper in Nature Health has gained significant visibility, with an Altmetric score now exceeding 590. It has also attracted considerable attention in the mainstream media, not all of which has accurately reflected the nuances of the spatial exposomic approach. In this context, we published a correspondence to clarify certain points and ensure the work was interpreted as intended, while situating it within the emerging exposomic framework: Bertani, S., Pineau, P., De
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