top of page

Latest Publications


IFN-gene signatures in B cells following influenza A and B virus infection and influenza vaccination
New publication for HKU-Pasteur’s Wuji Zhang ! Published in EMBO Molecular Medicine , the study explores how the human immune system responds to influenza vaccination and natural infection by dissecting the molecular features of influenza‑specific B cells. Using single‑cell RNA sequencing, the team compared responses to influenza A and B viruses and uncovered striking differences—particularly a strong interferon‑driven signature in B cells from influenza B patients. Their fin


Prof. Leo Poon's team develops novel live-attenuated vaccine that blocks coronavirus transmission with a single intranasal dose
The vaccine not only prevents severe disease, but also effectively blocks viral transmission in animal models, offering a promising strategy for pandemic preparedness against future coronavirus threats. A research team at the LKS Faculty of Medicine, the University of Hong Kong (HKUMed), has developed a novel live-attenuated vaccine candidate, cb1, capable of generating broad immunity against a wide range of beta-coronaviruses with a single intranasal dose. The vaccine not on


Resurgence of Zoonotic Highly Pathogenic Avian Influenza A(H5N1) Virus in Cambodia
New correspondance from Dr. Vijaykrishna Dhanasekaran o n the New England Journal of Medicine , this correspondance investigates the resurgence of highly pathogenic avian influenza (HPAI) A(H5N1) virus infections in Cambodia after nearly a decade of no reported human cases. To the Editor: After a decade of no reported human cases, Cambodia faces a resurgence of highly pathogenic avian influenza (HPAI) A(H5N1) virus infections, with an overall mortality of 38%. Cases have occ
bottom of page
